Lee Hepner (November 24, 1920 – July 24, 1986) was a Canadian teacher and orchestral conductor.
Hepner was born in Edmonton, Alberta. After organizing the Edmonton Pops Orchestra in 1947, he was principal conductor of the University of Toronto Symphony Orchestra (1949-1950). He was the first Music Director of the Edmonton Symphony Orchestra (1952-1960), and subsequently was Music Director of the McMaster Operatic Society (1961-1967), the Hamilton Philharmonic Orchestra (1962-1969), and the Hamilton Opera Company (1966-1972). He taught music at Queens College, New York, and at McMaster University from 1961 until his death in Vancouver, British Columbia. He founded the McMaster Symphony Orchestra in 1973.